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There’s another debut on tap for Thursday’s MLB slate as Luis Castillo is set to make his first start for the Chicago White Sox (59-54) after being acquired earlier this week from the Seattle Mariners. Castillo and the White Sox will face the Boston Red Sox (62-51) in the series finale at Fenway Park as the Red Sox go for the three-game sweep.

The Red Sox extended their winning streak to seven games Wednesday night with a 4-0 shutout victory over the White Sox. Boston starter Sonny Gray allowed just three hits and struck out eight batters over six innings, while the bullpen recorded six strikeouts in three innings of work to close out the game. Wilyer Abreu hit his 20th home run of the season and now has three long balls through the first two games of this series after hitting two in Tuesday’s dominant 14-2 win.

All-Star left-hander Ranger Suárez is scheduled to take the mound for the Red Sox in Thursday night’s series finale as he looks to help Boston complete the sweep and spoil Castillo’s White Sox debut. Castillo is a three-time All-Star and was once a Cy Young contender, but the 2026 season hasn’t been his best. The 33-year-old owns a 3-9 record with a 5.06 ERA across 20 appearances, including 17 starts.

White Sox vs. Red Sox Current Odds

The Red Sox have been one of the hottest teams in baseball for quite some time, and Hard Rock Bet Sportsbook lists Boston as the home favorite for Thursday night’s series finale as it looks to extend its winning streak to eight games:

  • Moneyline: Red Sox -190, White Sox +180
  • Run Line: Red Sox -1.5 (+110), White Sox +1.5 (-120)
  • Total (Runs): Over 8.5 (-110), Under 8.5 (+100)

Hard Rock Bet’s 10¢ Summer Sale continues throughout August, giving players reduced-vig dime lines on qualifying pregame MLB Moneyline, Run Line, and Total markets. Eligible odds are automatically adjusted, so no opt-in is required.

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White Sox vs. Red Sox Predictions

It’s been all Red Sox through the first two games of this series, but the White Sox have plenty of talent capable of making things interesting Thursday night. Head over to Hard Rock Bet Sportsbook to get in on the baseball betting action and check out the Stats Hub for valuable information on both teams and their players to help make picks for the game like the one below:

Red Sox vs. White Sox Best Bet: Wilyer Abreu Over 0.5 RBIs (+120)

Wilyer Abreu is beginning to heat up at the plate after a quiet month of July. He’s now batting .400 through his first four games of August and .348 with five home runs and five RBIs since July 30. Abreu has homered in three straight games entering Thursday, including a two-home run performance in Tuesday’s series opener, and has recorded at least one RBI in each of his last three games.

Abreu will face newly acquired White Sox starter Luis Castillo, against whom he’s 1-for-4 with a double in their all-time head-to-head meetings. However, he went 0-for-2 with a lineout and a groundout against him earlier this season on June 19, when Castillo was still a member of the Mariners. Castillo pitched four innings out of the bullpen in that matchup and allowed seven hits and five runs, four of which were earned, in a game Boston won 6-2.

Castillo has endured an overall difficult season, including posting a 5.48 ERA across four starts in July. He allowed 29 hits and 14 earned runs, including seven home runs, over 23 innings during the month. He surrendered 11 hits and five earned runs, including two home runs, in his last start against the Los Angeles Dodgers on July 28 while he was still with Seattle.

While the career sample against Castillo is small, Abreu is swinging a hot bat and notably has 15 home runs and 36 RBIs against right-handed pitchers this season. For reference, he has 20 home runs and 57 RBIs overall, so the majority of his production has come against righties. Abreu typically bats third in the Red Sox lineup, which creates plenty of opportunities for him to drive in runs even when he’s not hitting home runs, especially against a struggling pitcher like Castillo.

  • Red Sox vs. White Sox Player Prop Pick for Aug. 6: Wilyer Abreu Over 0.5 RBIs (+120)

Top 5 Most-Bet Player Props for CWS-BOS

Abreu has four home runs over his last three games, so his home run prop is attracting plenty of attention as the most-bet player prop for Thursday night’s series finale at Fenway Park:

  1. Wilyer Abreu – Over 0.5 Home Runs
  2. Ranger Suárez – Over 5.5 Strikeouts
  3. Willson Contreras – Over 0.5 Home Runs
  4. Willson Contreras – Over 0.5 Hits
  5. Wilyer Abreu – Over 1.5 Total Bases

White Sox vs. Red Sox Game Info

  • 📍 Where: Fenway Park, Boston, MA
  • 📅 Date: Thursday, Aug. 6
  • First Pitch: 7:10 PM ET
  • 📺💻 TV/Streaming: MLB.TV
  • Probable Pitchers:
    • White Sox: Luis Castillo
    • Red Sox: Ranger Suárez

More Ways to Bet

One swing can cash your ticket, but until then, Florida players can keep things interesting with Real Money Games powered by Past Motor Racing, only on Hard Rock Bet. It’s another way to stay engaged between plate appearances.

Referenced odds are subject to change.

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Michael Hennelly

Michael has been an active sports contributor for multiple publications since graduating from Penn State in 2024. While sports play a major role in his life (in the best way), he also enjoys spending time with family and friends. Contact Michael at [email protected].